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Comparison of the immunophenotypes of purified CML cells cultured in standard medium alone and CML cells treated with CI (A23187). Cells were cultured for 4 days, harvested, and then analyzed for expression of DC surface markers HLA-A, B, and C, DR, CD80, CD86, CD40, CD54, and CD83. Open histograms represent the isotype-matched control, whereas solid histograms symbolize staining for the different antibodies. Untreated progenitor cells stained negatively for HLA-DR in this patient.
