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In vivo hepatic distribution of fluorescently labeled ONs. Rats received 200 μg of 5′ fluorescein-labeled chimeric ONs encapsulated in anionic liposomes or complexed with PEI by single bolus tail vein injection. At the indicated times, their livers were processed and examined by confocal microscopy. Lip, liposomes. (Bar = 100 μm.)
