Table 4.
Kidney and liver weight 4 weeks after injection of streptozotocin or vehicle
| Long-Evans
|
Brattleboro
|
ANOVA
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Cont, n = 8 | DM, n = 8 | DM/Cont | Cont, n = 7 | DM, n = 8 | DM/Cont | S | D | I | |
| Kidney weight | 1.82 ± 0.03 | 3.33 ± 0.17*** | 1.83 | 2.05 ± 0.15 | 2.67 ± 0.09*** | 1.30 | c | c | |
| Liver weight | 10.15 ± 0.14 | 12.88 ± 0.26*** | 1.27 | 10.13 ± 0.26 | 11.66 ± 0.42*** | 1.15 | a | c | a |
Values are means ± SEM in g/300 g body weight. ANOVA: S, strain effect; D, diabetes effect; I, interaction; a, P < 0.05; c, P < 0.001. Fisher’s post hoc test: ∗∗∗, P < 0.001 vs. Cont in each strain.