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Accumulation of p53 (A) and ubiquitinated proteins (B) in epoxomicin-treated cells. (A) α-p53 immunoblot analyses of HUVECs treated with 100 nM epoxomicin (Epx), 5 μM lactacystin (Lac), or vehicle (ctrl) for 6 hr. (B) α-Ubiquitin immunoblot analyses of HeLa cells treated with 10 μM epoxomicin or peptide inhibitor Z-LLL-H for 2 hr.
