Abstract
A three year old Holstein dairy cow fed a ration containing a copper supplement died of chronic copper poisoning. The concentration of copper in the liver was 331 ppm (wet weight). The typical lesions of chronic copper toxicity including icterus, hepatic fibrosis and hemoglobinemic nephrosis were found at necropsy. The chronic copper toxicity was not considered to be a herd problem since the liver copper concentration in a slaughtered cull animal and blood samples taken from five animals in the same herd were within normal limits.
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Selected References
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- Ishmael J., Gopinath C., Howell J. M. Experimental chronic copper toxicity in sheep. Histological and histochemical changes during the development of the lesions in the liver. Res Vet Sci. 1971 Jul;12(4):358–366. [PubMed] [Google Scholar]
- Stogdale L. Chronic copper poisoning in dairy cows. Aust Vet J. 1978 Mar;54(3):139–141. doi: 10.1111/j.1751-0813.1978.tb05530.x. [DOI] [PubMed] [Google Scholar]
- TODD J. R. Chronic copper poisoning in farm animals. Vet Bull. 1962 Sep;32:573–580. [PubMed] [Google Scholar]
- Tontis A., König H., Luginbühl H. Zur Pathologie der chronischen Kupfervergiftung beim Schaf: Beobachtungen an 14 Spontanfällen. Schweiz Arch Tierheilkd. 1980 Feb;122(2):107–116. [PubMed] [Google Scholar]
- Weiss E., Baur P. Experimentelle Untersuchungen zur chronischen Kupfervergiftung des Kalbes. Zentralbl Veterinarmed A. 1968 Mar;15(2):156–184. [PubMed] [Google Scholar]