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. 2007 Jan 15;2:2. doi: 10.1186/1747-1028-2-2

Figure 1.

Figure 1

Possible roles of αB-crystallin in SCFFbx4-Cyclin D1 complex assembly. A. αB-crystallin serves as a bridge between SCFFbx4 and Cyclin D1. B. αB-crystallin and Fbx 4 cooperatively bind Cyclin D1. C. The binding of αB-crystallin induces conformational change in Fbx4 that provides the structural basis for the complex formation.