Table 4.
Best-Measured Acuity in Amblyopic Eye According to Baseline Factors (N=84)
N | Mean (SD*) Lines Improved from Baseline to Visit of Best- Measured Acuity | P Value† | Resolution at Visit of Best- Measured Acuity (IOD‡ within 1 line) n(%) | P Value† | |
---|---|---|---|---|---|
Age (years) | 0.88 | 0.40 | |||
3-<4 | 7 | 3.3 (1.8) | 1 (14) | ||
4-<5 | 25 | 2.5 (1.5) | 7 (28) | ||
5-<6 | 35 | 3.0 (2.1) | 12 (34) | ||
6-<7 | 17 | 2.9 (1.6) | 3 (18) | ||
Degree of Anisometropia§ | 0.07 | 0.03 | |||
0.50 to <1.00D ∥ | 7 | 3.1 (1.2) | 4 (57) | ||
1.00 to <2.00D | 11 | 2.8 (1.5) | 5 (45) | ||
2.00 to <3.00D | 13 | 3.5 (1.9) | 5 (38) | ||
3.00 to <4.00D | 24 | 2.6 (2.0) | 5 (21) | ||
>=4.00D | 26 | 2.8 (1.9) | 2 (8) | ||
Baseline Amblyopic Eye Acuity | 0.21 | 0.02 | |||
20/40 | 9 | 1.3 (1.1) | 2 (22) | ||
20/50 | 9 | 2.9 (1.1) | 6 (67) | ||
20/63 | 19 | 3.0 (1.6) | 8 (42) | ||
20/80 | 16 | 2.8 (1.6) | 2 (13) | ||
20/100 | 13 | 3.8 (2.2) | 4 (31) | ||
20/125 | 10 | 3.4 (2.2) | 1 (10) | ||
20/160-20/250 | 8 | 2.1 (1.7) | 0 | ||
Anisometropia Definition Met | 0.54 | 0.66 | |||
Spherical equivalent only (≥0.50D difference) | 67 | 3.0 (1.9) | 17 (25) | ||
Spherical equivalent and cylinder | 14 | 2.4 (1.3) | 4 (29) | ||
Cylinder only (≥1.50D difference) | 3 | 2.3 (1.2) | 2 (67) |
SD = Standard Deviation
P value for improvement to best-measured acuity outcome from analysis of covariance adjusted for baseline acuity, P value for resolution outcome from logistic regression analysis adjusted for baseline acuity
Interocular acuity difference evaluated using better sound eye at baseline or visit of bestmeasured amblyopic eye acuity
3 patients meeting only cylinder criteria are not included
D = diopter
This table does not include data on the additional long-term follow-up visit (4-6 months) for patients whose amblyopia resolved.