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. Author manuscript; available in PMC: 2007 Feb 2.
Published in final edited form as: Free Radic Biol Med. 2006 Sep 29;42(1):1–14. doi: 10.1016/j.freeradbiomed.2006.08.028

Table 2.

NAME SIZE (KDA) LOCALIZATION BACTERIAL HOMOLOG SOME KNOWN AND POSSIBLE FUNCTIONS
Ubiquitin 8 Cytosol/nucleus — Nonlysosomal degradation pathways
HSP 27 27 Cytosol/nucleus Regulator of actin cytoskeleton; molecular chaperone; cytoprotection
Heme 32 Bound to ER, Degradation of heme to bilirubin;
oxygenase extends to cytoplasm — resistance to oxidant stress
HSP 47 47 ER — Collagen chaperone
HSP 60 60 Mitochondria Gro EL Molecular chaperone
HSP 70 72 Cytosol/nucleus Dna K Highly stress inducible; involved in cytoprotection against diverse agents
73 Cytosol/nucleus — Constitutively expressed chaperone
HSP 90 90 Cytosol/nucleus htpG Regulation of steroid hormone activity
HSP 110 110 Nucleolus/cytosol Clp family Protects nucleoli from stress