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. Author manuscript; available in PMC: 2007 Feb 2.
Published in final edited form as: Nat Struct Mol Biol. 2005 Nov 6;12(12):1086–1093. doi: 10.1038/nsmb1015

Figure 1.

Figure 1

RNAP/Tgt structure. (a) Experimental 3.5Å resolution and |FTgt - Fnati| (3.0σ level both) omit ED map (green) superimposed on the RNAP1/Tgt structure. The residues (balls-and-sticks) and protein backbone (ribbon diagram) of the β and β′ subunits are shown in yellow and gray, respectively. In this and following figures, cMG1, cMG2, and tMG designate high- and low-affinity catalytic and Tgt-bound Mg2+ ions, respectively. (b) Overall view of the RNAP/Tgt complex structure showing that Tgt binds within the secondary channel in close vicinity to the active site (marked by cMG1, magenta sphere).