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. Author manuscript; available in PMC: 2007 Feb 5.
Published in final edited form as: Am J Cardiol. 2006 Jul 7;98(5):649–652. doi: 10.1016/j.amjcard.2006.03.045

Table 3.

Diastolic blood pressure variability according to quartiles of C-reactive protein and tumor necrosis factor- alpha. Results of multivariable-adjusted linear regression models.

Inflammatory Markers Mean* (95% CI) Within-Subject Standard Deviation of Daytime Diastolic Blood Pressure: Mean (95% CI) Within-Subject Standard Deviation of Nighttime Diastolic Blood Pressure: Mean (95% CI) Within-Subject Standard Deviation of 24-hour Diastolic Blood Pressure:
CRP Quartiles
(< 0.5 mg/L) 8.0 (7.3, 8.8) 6.7 (5.8, 7.6) 9.9 (9.1, 10.7)
(0.5 mg/L to < 1.2 mg/L) 7.9 (7.2, 8.6) 7.8 (7.0, 8.7) 9.7 (8.9, 10.4)
(1.2 mg/L to < 2.9 mg/L) 9.0 (8.3, 9.7) 7.8 (7.0, 8.7) 10.4 (9.7, 11.2)
(≥ 2.9 mg/L) 9.4 (8.7, 10.1) 8.6 (7.8, 9.5) 11.0 (10.2, 11.7)
P for linear trend = .003 P for linear trend = .01 P for linear trend = .03
TNF-α Quartiles
(< 0.7 pg/ml) 8.1 (7.4, 8.8) 7.8 (7.0, 8.7) 9.9 (9.1, 10.6)
(0.7 pg/ml to < 0.9 pg/ml) 8.4 (7.7, 9.1) 7.7 (6.9, 8.6) 10.4 (9.7, 11.1)
(0.9 pg/ml to < 1.4 pg/ml) 8.8 (8.1, 9.6) 6.9 (6.0, 7.7) 10.1 (9.3, 10.8)
(≥ 1.4 pg/ml) 9.1 (8.4, 9.7) 8.4 (7.6, 9.2) 10.7 (10.0, 11.4)
P for linear trend = .04 P for linear trend = .52 P for linear trend = .28
*

Means adjusted for age, sex, race, BMI, quartiles of the other inflammatory marker, and mean daytime diastolic BP

Means adjusted for age, sex, race, BMI, quartiles of the other inflammatory marker, and mean nighttime diastolic BP

Means adjusted for age, sex, race, BMI, quartiles of the other inflammatory marker, and mean 24-hour diastolic BP

BMI = body mass index; BP = blood pressure; CRP = C-reactive protein; TNF-α = tumor necrosis factor-alpha