Table 1.

GSTT2 polymorphisms and colorectal cancer risk

Locus	HWE	MAF	Genotype	Healthy controls (N = 568)	CRC patients (N = 436)	p	OR(95% CI)
-537	0.999	0.42	GG	203 (35.7%)	127 (29.1%)	0.025	1.373 (1.041–1.810)
			GA or AA	365 (64.3%)	309 (70.9%)
-277	0.548	0.07	TT	489 (86.1%)	388 (89.0%)	0.125	0.735 (0.495–1.090)
			TC or CC	79 (13.9%)	48 (11.0%)
-158	0.314	0.03	GG	522 (91.9%)	416 (95.4%)	0.032	0.539 (0.307–0.947)
			GA or AA	46 (8.1%)	20 (4.6%)

Adjusted for age and sex; HWE: Hardy-Weinberg equilibrium for controls; MAF: Minor allele frequency

Dominant model: Homozygote of major allele vs. heterozygote and homozygote of minor allele