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. 2007 Jan 26;6:1. doi: 10.1186/1477-3163-6-1

Table 1.

High frequency mtDNA variants among three epithelial ovarian tumor subtypes

Mitochondrial genes/regions Nucleotide Position np Mutation Frequency
Total # of cases 102
% frequency in subtypes

Serous Endometrioid Mucinous
D-loop 16487 del A1 73 87 69 39
D-loop T16519C 52 47 74 50
D-loop A73G 59 91 92 89
D-loop A263G 93 36 60 72
12S rRNA 984 del C1 58 73 72 72
C984G1 16
12S rRNA A1438G 95 91 95 94
tRNAval 1648 del T1 93 98 92 72
tRNAval 1653 del T1 20 98 87 100
T1653A1 76
tRNAval 1659 del T1 89 78 95 94
COX2 8237 del A1 68 82 49 67
ATP6 A8860G 96 96 97 83
ATP6 8877 del T1 49 40 44 78
ATP6 T8889 A1 51 93 87 83
T8889C1 16
8889del T1 24

1 Not reported in mtDNA databank.

The frequency % of the three subtypes at np 984,1653 and 8889 represents the sum total of the different types of mutations occurring at that position.