Table 1.
Mitochondrial genes/regions | Nucleotide Position np | Mutation Frequency Total # of cases 102 |
% frequency in subtypes | ||
Serous | Endometrioid | Mucinous | |||
D-loop | 16487 del A1 | 73 | 87 | 69 | 39 |
D-loop | T16519C | 52 | 47 | 74 | 50 |
D-loop | A73G | 59 | 91 | 92 | 89 |
D-loop | A263G | 93 | 36 | 60 | 72 |
12S rRNA | 984 del C1 | 58 | 73 | 72 | 72 |
C984G1 | 16 | ||||
12S rRNA | A1438G | 95 | 91 | 95 | 94 |
tRNAval | 1648 del T1 | 93 | 98 | 92 | 72 |
tRNAval | 1653 del T1 | 20 | 98 | 87 | 100 |
T1653A1 | 76 | ||||
tRNAval | 1659 del T1 | 89 | 78 | 95 | 94 |
COX2 | 8237 del A1 | 68 | 82 | 49 | 67 |
ATP6 | A8860G | 96 | 96 | 97 | 83 |
ATP6 | 8877 del T1 | 49 | 40 | 44 | 78 |
ATP6 | T8889 A1 | 51 | 93 | 87 | 83 |
T8889C1 | 16 | ||||
8889del T1 | 24 |
1 Not reported in mtDNA databank.
The frequency % of the three subtypes at np 984,1653 and 8889 represents the sum total of the different types of mutations occurring at that position.