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. 2007 Jan 25;7:18. doi: 10.1186/1471-2407-7-18

Table 3.

Analysis of clinical predictive factors.

Clinical predictive factors for response
Tumor control (SD, CR, PR) Brain progression (PD) P value

Lung Cancer 16 7 0.363
All the others 29 7
Males 25 7 0.321
Females 17 10
KPS <70 6 10 < 0.0001
KPS ≥70 29 4
No previous chemotherapy 20 5 0.758
Previous chemotherapy 25 9
No extracranial disease 25 2 0.012
Extracranial disease 20 12
Age > 65 years 6 10 <0.0001
Age ≤65 years 39 4

RPA as a predictive factor for response

Tumor control (SD, CR, PR) Brain progression (PD) P value

RPA 1 14 0 < 0.0001
RPA 2 25 4
RPA 3 6 10