Table 7.
Most common and serious Adverse events During TMZ/WBRT treatment according to Common Toxicity Criteria extended by National Cancer Institute, (NCI CTC) in the 59 enrolled patients.
| Grade 2 | Grade 3 | Grade 4 | ||||
| Toxicity | No. pts | % | No. pts | % | No. pts | % |
| Neutropenia | 15 | 25 | 9 | 15 | - | - |
| Thrombocytopenia | 4 | 7 | 2 | 3 | 1 | 1 |
| Anemia | 7 | 12 | 8 | 13 | - | - |
| Alopecia | 2 | 3 | - | - | - | - |
| Vomiting | 6 | 10 | 2 | 3 | ||
| hand and foot syndrome | 2 | 3 | - | - | - | - |
| Headache | 5 | 8 | 1 | 1 | - | - |
| Nausea | 5 | 8 | 2 | 3 | - | - |
| Tremor | 4 | 7 | 2 | 3 | - | - |
| Nerosensory | 3 | 5 | - | - | - | - |
| Fatigue | 7 | 12 | 2 | 3 | - | - |
| Rash | 8 | 13 | 3 | 5 | - | - |