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Effect of treatment with GHRH antagonist JMR-132 given s.c. at a dose of 10 μg/day (column 3), docetaxel given i.p. at a concentration of 20 milligrams per kilogram of body weight on days 1 and 5 (column 2), or the combination of JMR-132 with docetaxel (column 4) on the tumor weight of MX-1 human breast cancer xenografted s.c. into nude mice. Vertical bars indicate SE. *, P < 0.001 vs. control; **, P < 0.001 vs. control (column 1) and the groups receiving single agents.
