Fig. 2.

Superposition of the NTD β-propeller blades. (A) Schematic drawing of a β-propeller fold indicating the β-strands and loops of one β-propeller blade. (B) Coil representation of the structural alignment of the seven blades of the β-propeller. Blades are colored as in Fig. 1. As a reference, the Cα atoms of blade 2 are shown as orange spheres. A 90°-rotated view is shown on the right. (C) Structure-based sequence alignment of the blades. The β-strands are indicated above the sequence. Similar residues are shown in red, and the residues of each blade that participate in β-sheet hydrogen bonds are underlined in gray.