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Extended neutral net for the HP structure in Fig. 1, with 146 sequences. Same as Fig. 2a, except that native stabilities of the sequences are now measured by free energy of folding (Eq. 3) and that multiply-degenerate sequences (degeneracy g ≤ 6) are included. Numbers of sequences with g = 1, 2, 3, 4, 5, and 6 in this net are 48, 22, 16, 27, 14, and 19, respectively. The vertical bars and numbers on the right indicate the range of stability levels for sequences with different gs.
