Table 4.
Characteristics of the medical patients
| Uncomplicated sepsis (n = 8) |
Septic shock (n = 12) |
Sepsis-induced ARDS (n = 9) |
Mechanical ventilation (n = 11) |
Controls (n = 33) |
P value | |
| Age (years, mean ± SEM) | 50.8 ± 4.9 | 56 ± 5.6 | 43.2 ± 5.8 | 57.5 ± 4.9 | 37.1 ± 1.7 | <0.008a |
| Male/Female (percentage) | 50.0/50.0 | 58.3/41.7 | 44.4/55.6 | 36.4/63.6 | 48.5/51.5 | 0.7b |
| APACHE II score (percentage) | 13.6 ± 2.2 | 21 ± 2.2 | 21.5 ± 1.2 | - | - | 0.1 |
| Maximum SOFA score (percentage) | 4.7 ± 0.7 | 9.9 ± 1.0 | 12 ± 0.8 | - | - | <0.001a |
| Organ dysfunction (percentage) | ||||||
| 0 | 50 | 25 | 0 | - | - | - |
| 1 | 0 | 16.7 | 77.8 | - | - | - |
| 2 | 25 | 41.7 | 0 | - | - | - |
| 3 | 25 | 16.7 | 22.2 | - | - | - |
| Organ failure (percentage) | ||||||
| 0 | 25 | 0 | 0 | - | - | - |
| 1 | 62.5 | 25 | 0 | - | - | - |
| 2 | 12.5 | 41.7 | 55.6 | - | - | - |
| 3 | 0 | 33.3 | 33.3 | - | - | - |
| 4 | 0 | 0 | 11.1 | - | - | - |
| Mortality in 28 days (percentage) | 37.5 | 75 | 77.8 | - | - | - |
| Neutrophil apoptosis (mean percentage ± SEM) | 57 ± 3.2 | 38 ± 3.7 | 28 ± 3.3 | 53 ± 3.0 | 69 ± 1.1 | <0.001a |
aP value from the comparisons using analysis-of-variance test; bp value from the comparisons using χ2 test. APACHE II, Acute Physiology and Chronic Health Disease Classification System II; ARDS, acute respiratory distress syndrome; SEM, standard error of the mean; SOFA, sequential organ failure assessment.