Table 1.
Demographic features of study of patients
| All patients (n = 331) | PiCCO (n = 192) | PAC (n = 150) | p value | |
| At ICU admission | ||||
| Gender (male) | 58.9% | 57.3% | 60.0% | 0.66 |
| Age in years | 67 (54, 75) | 64 (47, 74) | 68 (57, 76) | 0.0037 |
| NYHA: III, IV | 11.5% | 10.9% | 12.0% | 0.86 |
| IHD | 31.1% | 32.3% | 28.7% | 0.48 |
| COPD | 16.0% | 14.1% | 18.7% | 0.30 |
| Diabetes | 22.1% | 25.0% | 19.3% | 0.24 |
| Previous renal function | ||||
| Normal | 58.6% | 59.4% | 58.7% | 0.91 |
| Impaired | 22.4% | 22.4% | 22.0% | >0.99 |
| ESRF | 3.9% | 4.7% | 2.7% | 0.40 |
| Unknown | 15.1% | 13.5% | 16.7% | 0.45 |
| SAPS II | 49 (37, 61) | 49 (37, 61) | 47 (37, 61) | 0.91 |
| At study inclusion | ||||
| Vasopressors | 73.4% | 75.0% | 71.3% | 0.46 |
| Inotropic drugs | 22.1% | 13.0% | 37.3% | <0.0001 |
| Heart rate (beats per minute) | 98 (84, 115) | 99 (85, 118) | 97 (84, 111) | 0.48 |
| MAP (mm Hg) | 75 (68, 85) | 76 (70, 85) | 73 (63, 84) | 0.0086 |
| Cardiac index (litres/minute per m2) | 3.0 (2.3, 4.0) | 3.2 (2.6, 4.5) | 2.6 (2.1, 3.5) | <0.0001 |
| CVP (mm Hg) | 12 (8, 15) | 12 (9, 16) | 11 (8, 14) | 0.011 |
| ITBI (ml/m2) | - | 967 (768, 1,140) | - | |
| ELWI (ml/kg) | - | 8.9 (6.6, 13.0) | - | |
| PAOP (mm Hg) | - | - | 17 (12, 22) | |
| Mechanical ventilation | 81.6% | 80.2% | 84.0% | 0.40 |
| PEEP (cm H2O) | 5 (5, 10) | 6 (5, 10) | 5 (5, 8) | 0.21 |
| PaO2/FiO2 ratio (Torr) | 186 (125, 279) | 191 (126, 279) | 185 (125, 285) | 0.87 |
| RRT | 21.4% | 26.6% | 16.7% | 0.036 |
| Urea (mmol/l) | 12.1 (7.1, 19.0) | 12.0 (7.1, 18.7) | 12.2 (7.1, 19.1) | 0.91 |
| Creatinine (μmol/l) | 142 (100, 231) | 151 (100, 231) | 137 (97, 230) | 0.42 |
Values are presented as medians (with 25th and 75th percentiles) or as percentages. COPD, chronic obstructive pulmonary disease; CVP, central venous pressure; ELWI, extra-vascular lung water index; ESRF, end-stage renal failure; ICU, intensive care unit; IHD, ischaemic heart disease; ITBI, intra-thoracic blood volume index; MAP, mean arterial pressure; NYHA, New York Heart Association; PAC, pulmonary artery catheter; PAOP, pulmonary artery occlusion pressure; PaO2/FiO2, partial pressure of oxygen in arterial blood/fraction of inspired oxygen; PEEP, positive end-expiratory pressure; PiCCO, pulse contour cardiac output; RRT, renal replacement therapy; SAPS II, simplified acute physiology score.