Figure 1.

Effects of critical illness on plasma PYY and CCK concentrations. Effects of critical illness on plasma (a) PYY and (b) CCK concentrations during fasting and duodenal nutrient infusions of 1 kcal/minute (ICU patients, n = 9; healthy subjects, n = 13) and 2 kcal/minute (ICU patients, n = 10; healthy subjects, n = 11) compared with healthy age- and gender-matched control group. ICU patients: closed diamond, solid line; healthy subjects: open circle, solid line. Fasting and nutrient-stimulated PYY and CCK concentrations were higher in patients compared with the healthy control group. *P < 0.05, **P < 0.001 versus healthy subjects. CCK, cholecystokinin; ICU, intensive care unit; PYY, peptide YY.