Table 1.
Disease group | Female/male ratio (percentage) | Age in years (range) | OD α-actinin binding (range) | No. (percentage) with positive α-actinin binding |
RA (n = 68) | 65/35 | 67.7 (24 to 85) | 0.102 (0.06 to 0.26)a | 8 (12)a |
SLE (n = 99) | 92/8 | 35.7 (15 to 73) | 0.112 (0.05 to 0.63)a | 20 (20)a |
WG (n = 85) | 57/43 | 49.1 (17 to 76) | 0.053 (0.04 to 0.08) | 0 (0) |
ANA-positive (n = 142) | 63/37 | 52.2 (6 to 78) | 0.09 (0.06 to 0.90) | 46 (32)a |
aIndicates significant difference compared with WG category. Numbers represent mean values (range) unless otherwise indicated. ANA, anti-nuclear antibody; OD, optical density; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; WG, Wegener's granulomatosis.