Table 3.
Correlation between α-actinin-binding antibody levels and clinical findings in patients with SLE
Disease feature | Spearman's rho | p value |
Anti-dsDNA Ab ELISA (IU/ml) | 0.638 | 0.0001a |
Anti-dsDNA Ab EliA (IU/ml) | 0.601 | 0.0001a |
Total SLEDAI score | 0.378 | 0.0001a |
ESR | 0.254 | 0.035 |
CRP (mg/l) | 0.236 | 0.048 |
C3 (mg/l) | -0.102 | 0.522 |
C4 (mg/l) | -0.078 | 0.623 |
Age (years) | -0.197 | 0.051 |
Creatinin clearance (ml/minute) | 0.339 | 0.199 |
Proteinuria (g/24 hours) | 0.182 | 0.484 |
Renal SLICC score | -0.031 | 0.796 |
Total SLICC | -0.385 | 0.0053 |
aSignificant results (p < 0.005) after the Bonferroni correction. C3, complement factor 3; C4, complement factor 4; CRP, C-reactive protein; EliA, fluorescence enzyme immunoassay test for anti-double-stranded DNA (Phadia GmbH); ELISA, enzyme-linked immunosorbent assay; ESR, erythrocyte sedimentation rate; SLE, systemic lupus erythematosus; SLEDAI, Systemic Lupus Erythematosus Disease activity index; SLICC, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemic lupus erythematosus.