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Relative orientation of cis-natural antisense transcript pairs. (A) Headto-head (5′ to 5′) overlap involving 5′-untranslated regions and coding exons. (B) Tail-to-tail (3′ to 3′) overlap. (C) Fully overlapping (one gene included entirely within the region of the other). Coloured boxes represent exons, grey boxes represent untranslated regions.
