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Spatial organization of cytokine loci. Schematic representation of the murine Th2 (Il3/Rad50/Il13/Il4), interferon-γ (Ifnγ) and Th1 (Ltβ/Tnfα/Ltα) loci used in 3C chromosome-interaction analyses by Flavell and co-workers (Spilianakis et al, 2005). Vertical arrows on the top represent the DNaseI-hypersensitive sites so far characterized at the Th2 locus.
