Figure 4.

Immunohistochemical localization of BrdUrd-labeled MSCs in forebrain. Hematoxylin/eosin (A)- or anti-BrdUrd (B)-stained serial sections of striatum and lateral ventricle, ipsilateral to the injection site at bregma. (C) High power magnification of BrdUrd-labeled cells in the external capsule. Photomicrograph is from same section as B but shows a more lateral field. (D) MSC-derived astrocyte in the molecular layer of the hippocampus double labeled with anti-BrdUrd and anti-GFAP (black). Arrows, BrdUrd-labeled nuclei; arrow-heads, nuclei negative for BrdUrd-labeling. (A and B, ×40; C, ×400; D, ×1,000.)