Table 1.
Mechanical properties of normal, gsg−/−, and mdx EDL
Parameter | Genotype
|
|||
---|---|---|---|---|
Mature normal | Young gsg−/− | Mature gsg−/− | Mature mdx | |
Lo, mm | 10.9 ± 0.2 | 8.9 ± 0.1 | 11.6 ± 0.1 | 11.5 ± 0.1 |
EDL weight, mg | 9.4 ± 0.1 | 4.7 ± 0.3 | 9.4 ± 0.4 | 15.0 ± 0.4 |
EDL CSA, mm2 | 1.8 ± 0.0 | 1.1 ± 0.1 | 1.7 ± 0.1 | 2.7 ± 0.1 |
Twitch force, mN | 123.3 ± 9.3 | 49.6 ± 5.5 | 136.5 ± 7.3 | 117.1 ± 10.5 |
Tetanic force, mN | 349.3 ± 11.2 | 150.5 ± 11.9 | 334.8 ± 9.5 | 355.3 ± 15.8 |
Tetanic force CSA, mN/mm2 | 19.3 ± 0.6 | 13.8 ± 1.1 | 19.9 ± 1.0 | 13.1 ± 0.7 |
Results are presented as mean ± SEM. CSA, cross-sectional area.