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. 1999 Sep 14;96(19):10812–10817. doi: 10.1073/pnas.96.19.10812

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Copyright © 1999, The National Academy of Sciences

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(A) Change in serum iron concentration after the i.v. infusion of damaged red blood cells in 10-wk-old Cp^+/+ and Cp^−/− mice. Results are expressed as means ± standard deviations, n = 8 per time point (∗, P < 0.001). (B) Change in serum iron concentration after i.v. infusion of damaged red blood cells. Arrow indicates time of infusion of ceruloplasmin (Cp) or apoceruloplasmin (apoCp) as 6 μg/100 μl of circulating blood volume. Results expressed as means ± standard deviations, n = 8 per time point (∗, P < 0.001). (C) Change in serum iron concentration after serial phlebotomy in 10-wk-old Cp^+/+ and Cp^−/− mice. Results are expressed as means ± standard deviations, n = 6 per time point (∗, P < 0.001). Arrow indicates timing of infusion of ceruloplasmin (Cp) or apoceruloplasmin (apoCp) as 6 μg/100 μl of circulating blood volume.