Table 1.
Mice | Hb, g/dl | Serum iron, μg/dl | TIBC, μg/dl | Transferrin saturation, % | Ferritin, ng/ml | Iron content, μg/g dry wt
|
|
---|---|---|---|---|---|---|---|
Liver | Spleen | ||||||
Cp+/+ | 14.1 ± 3.3 | 252 ± 25 | 477 ± 45 | 43 ± 7 | 112 ± 10 | 252 ± 64 | 224 ± 63 |
Cp−/− | 13.9 ± 3.4 | 245 ± 100 | 517 ± 30 | 33 ± 5 | 410 ± 103* | 666 ± 130* | 1,294 ± 94* |
Values are means ± standard deviations, n = 3 from each group at 1 year of age. Hb, hemoglobin; (Hb), TIBC, total iron binding capacity. Significant differences were observed between Cp+/+ and Cp−/− mice for serum ferritin, (∗, P < 0.001), liver tissue iron content, (∗, P < 0.001), and spleen tissue iron content (∗, P < 0.001 in all cases).