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. 1999 Sep 14;96(19):10812–10817. doi: 10.1073/pnas.96.19.10812

Table 2.

Iron absorption, distribution, and turnover in aceruloplasminemic mice

Mice Iron absorption, % total 59Fe dose absorbed Iron distribution
Plasma iron turnover, μg/dl/min
Organ % 59Fe absorbed Before phlebotomy After phlebotomy
Cp+/+ 16  ±  6 Liver 9  ± 1 1.6–2.3 3.4–4.2
Spleen 1  ± 0.1
RBC 50  ± 5
Cp−/− 12  ±  3 Liver 10  ± 2 2.2–2.6 1.6–2.2
Spleen 1
RBC 52  ± 4

Values are means ± standard deviations, n = 6 from each group. Plasma iron turnover was determined in Cp+/+ and Cp−/− mice before and after 7 days of serial phlebotomy. A significant difference was observed in plasma iron turnover between Cp+/+ and Cp−/− mice after phlebotomy (∗, P < 0.005).