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. 2006 Dec 22;4:37. doi: 10.1186/1741-7015-4-37

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Copyright © 2006 Jabba et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Tissue specificity of macrophage invasion. Transcripts of markers specific for or consistent with the presence of macrophages in stria vascularis, spiral ligament, spleen and liver of Slc26a4^+/-and Slc26a4^-/-mice at P34 and/or P86 were quantified by qRT-PCR. Significant changes between Slc26a4^+/-and Slc26a4^-/-mice are marked with an asterisk (*). Numbers between bars represent the number of animal pairs analyzed. Note that significant increases were mainly seen in stria vascularis, to a lesser degree in spiral ligament, but not in spleen or liver. These data suggest that macrophage invasion is specific to stria vascularis.