Table 3.
Genes that were expected to be expressed in stria vascularis.
| Slc26a4+/+ | Slc26a4-/- | |||||||
| No. | Gene | Description | Intensity | P | Intensity | P | Fold | Direction |
| 1 | Slc12a1 | Na+/2Cl-/K+ cotransporter | 14,664 | 12/12 | 10,656 | 12/12 | 1.33 | down |
| 2 | Atp1a1 | Na+/K+ ATPase, alpha | 7,276 | 9/15 | 5,440 | 9/15 | 2.06 | down |
| 3 | Atp1b1 | Na+/K+ ATPase, beta1 | 10,593 | 12/18 | 8,587 | 12/18 | 1.20 | |
| 4 | Atp1b2 | Na+/K+ ATPase, beta2 | 8,057 | 6/6 | 5,984 | 6/6 | 1.41 | down |
| 5 | Kcnq1 | K+ channel, alpha | 858 | 15/24 | 542 | 11/24 | 2.48 | down |
| 6 | Kcne1 | K+ channel, beta | 9,042 | 6/6 | 3,490 | 6/6 | 2.60 | down |
| 7 | Kcnma1 | K+ channel, BK | 270 | 10/18 | 159 | 9/18 | 1.72 | down |
| 8 | Kcnk1 | K+ channel | 2,667 | 6/6 | 1,670 | 6/6 | 1.92 | down |
| 9 | Slc26a4 | Pendrin | 1,136 | 3/3 | 619 | 3/3 | 1.84 | down |
| 10 | Kcnj10 | K+ channel | 17,169 | 3/3 | 17,005 | 3/3 | 1.01 | |
| 11 | Car2 | Carbonic anhydrase | 9,139 | 3/3 | 9,167 | 3/3 | 1.00 | |
| 12 | Gjb2 | Connexin 26 | 12,785 | 3/3 | 12,629 | 3/3 | 1.01 | |
| 13 | Gjb6 | Connexin 30 | 15,257 | 3/3 | 13,060 | 3/3 | 1.17 | |
| 14 | Sod1 | Superoxide dismutase | 4,149 | 14/15 | 3,538 | 14/15 | 1.21 | |
| 15 | Cat | Catalase | 3,520 | 6/6 | 4,686 | 6/6 | 1.12 | |
| 16 | Gpx1 | Glutathione peroxidase | 2,633 | 3/3 | 4,320 | 3/3 | 1.64 | up |
| 17 | Gpx3 | Glutathione peroxidase | 12,526 | 3/3 | 9,898 | 3/3 | 1.27 | |
| 18 | Gpx4 | Glutathione peroxidase | 11,224 | 6/6 | 10,421 | 6/6 | 1.06 | |
| 19 | Tyr | Tyrosinase | 3,520 | 6/6 | 4,686 | 6/6 | 1.16 | |
Genes that are expected to be expressed in marginal and spindle cells of stria vascularis (1–9) and genes that are expected to be expressed in intermediate and basal cells of stria vascularis (10–19) are listed. For parameters 'P', 'Fold' and 'Direction', see the Gene array section in Methods. Fold changes are given when a gene was called Present (P) in Slc26a4+/- or Slc26a4-/- samples in at least half of the available probes. The direction of the fold change is only given when it exceeded 1.30. Fold changes lower than 1.30 were not considered significant.