Table 5.
Markers for macrophages/dendritic cells.
| Slc26a4+/+ | Slc26a4-/- | |||||||
| No. | Gene | Description | Intensity | P | Intensity | P | Fold | Direction |
| 1 | Ptprc | Cd45 antigen | 226 | 3/3 | 946 | 3/3 | 4.19 | up |
| 2 | Cd83 | Cd83 antigen | 126 | 0/3 | 524 | 3/3 | 4.16 | up |
| 3 | Cd68 | Cd68 antigen | 170 | 3/3 | 1,344 | 3/3 | 7.90 | up |
| 4 | Cd14 | Cd14 antigen | 412 | 1/3 | 619 | 3/3 | 1.50 | up |
| 5 | H2-Aa | MHC class II | 264 | 5/12 | 1,019 | 9/12 | 4.00 | up |
| 6 | H2-Ab | MHC class II | 126 | 0/9 | 279 | 3/9 | 1.86 | up |
| 7 | H2-Eb1 | MHC class II | 429 | 0/3 | 1,010 | 3/3 | 2.35 | up |
| 8 | Lgals3 | Mac2 antigen | 91 | 2/6 | 1,866 | 5/6 | 13.49 | up |
| 9 | Itgax | Integrin alpha X | 125 | 0/3 | 375 | 3/3 | 3.00 | up |
| 10 | Emr1 | Mucin receptor | 750 | 3/3 | 1,547 | 3/3 | 2.06 | up |
| 11 | Lyzs | Lysozyme | 551 | 6/9 | 8257 | 9/9 | 11.78 | up |
| 12 | H2-K1 | MHC class I (D-region) | 1,607 | 13/18 | 4,062 | 15/18 | 2.06 | up |
| 13 | H2-K1 | MHC class I (K-region) | 1,828 | 6/12 | 2,883 | 6/12 | 1.54 | up |
| 14 | H2-K1 | MHC class I (Q-region) | 549 | 1/3 | 890 | 3/3 | 1.62 | up |
| 15 | C1r | Complement | 37 | 2/6 | 266 | 6/6 | 13.87 | up |
| 16 | C1s | Complement | 71 | 0/3 | 200 | 1/3 | ||
| 17 | C1qa | Complement | 355 | 1/3 | 2,905 | 3/3 | 8.19 | up |
| 18 | C1qb | Complement | 552 | 5/6 | 2,001 | 6/6 | 4.43 | up |
| 19 | C2 | Complement | 3,207 | 9/9 | 4,794 | 6/6 | 1.62 | up |
| 20 | C3 | Complement | 11 | 0/3 | 231 | 2/3 | 20.68 | up |
| 21 | C4 | Complement | 1,556 | 3/3 | 4,788 | 3/3 | 3.08 | up |
| 22 | C3ar1 | Complement receptor | 177 | 3/9 | 482 | 6/9 | 2.93 | up |
| 23 | Ctss | Cathepsin S | 2,304 | 3/3 | 7,394 | 3/3 | 3.21 | up |
| 24 | Ctsk | Cathepsin K | 170 | 1/3 | 377 | 3/3 | 2.21 | up |
| 25 | Ctsb | Cathepsin B | 4,172 | 12/15 | 6,576 | 12/15 | 1.90 | up |
| 26 | Msr2 | Macrophage scavenger receptor | 169 | 3/3 | 1140 | 3/3 | 6.75 | up |
| 27 | Mpeg1 | Macrophage expressed gene | 582 | 0/3 | 5,527 | 3/3 | 9.49 | up |
| 28 | Cst3 | Cystatin C | 5,562 | 3/3 | 8,652 | 3/3 | 1.56 | up |
| 29 | Fcgr1 | IgG receptor, high affinity | 98 | 0/6 | 163 | 5/6 | 1.70 | up |
| 30 | Fcgr2b | IgG receptor, low affinity | 112 | 2/15 | 377 | 7/15 | 3.94 | up |
Genes that can serve as markers macrophages/dendritic cells (1–10) and genes that are consistent with the presence of macrophages/dendritic cells (11–27) are listed. For parameters 'P', 'Fold' and 'Direction', see the Gene array section in Methods. Fold changes are given when a gene was called Present (P) in Slc26a4+/- or Slc26a4-/- samples in at least half of the available probes. The direction of the fold change is only given when it exceeded 1.30. Fold changes lower than 1.30 were not considered significant.