Table 6.
Slc26a4+/+ | Slc26a4-/- | |||||||
No. | Gene | Description | Intensity | P | Intensity | P | Fold | Direction |
1 | Tcra | T-cell receptor, alpha | 214 | 0/9 | 190 | 0/9 | ||
2 | Tcrb-V13 | T-cell receptor, beta V13 | 136 | 4/36 | 109 | 4/36 | ||
3 | Tcrb-J | T-cell receptor, beta V13 | 71 | 2/15 | 50 | 1/15 | ||
4 | Tcrg | T-cell receptor, gamma V4 | 54 | 0/15 | 43 | 0/15 | ||
5 | Cd3d | Cd3 antigen | 10 | 0/3 | 8 | 0/3 | ||
6 | Cd3e | Cd3 antigen | 139 | 0/6 | 74 | 0/6 | ||
7 | Cd3g | Cd3 antigen | 43 | 0/3 | 28 | 0/3 | ||
8 | Cd3z | Cd3 antigen | 182 | 4/24 | 139 | 3/24 | ||
9 | Cd4 | Cd4 antigen | 20 | 0/6 | 149 | 0/6 | ||
10 | Cd8a | Cd8 antigen | 144 | 4/15 | 143 | 4/15 | ||
11 | Cd8b | Cd8 antigen | 1,313 | 3/6 | 1,343 | 3/6 | ||
12 | Ncam1 | Cd56 | 562 | 8/21 | 654 | 12/21 | 1.16 | |
13 | Fcgr3 | IgG receptor, low aff, Cd16 | 162 | 2/3 | 401 | 3/3 | 2.48 | up |
14 | Sdc1 | Syndecan 1 (Cd138) | 77 | 3/12 | 72 | 3/12 | ||
15 | Cd19 | Cd19 antigen | 15 | 0/3 | 13 | 0/3 | ||
16 | Mpo | Myeloperoxidase | 159 | 0/3 | 73 | 0/3 | ||
17 | Defb1 | Beta-defensin 1 | 66 | 1/6 | 72 | 2/6 | ||
18 | Defb2 | Beta-defensin 2 | 23 | 0/3 | 14 | 0/3 | ||
19 | Defb3 | Beta-defensin 3 | 31 | 0/3 | 70 | 0/3 | ||
20 | Defb4 | Beta-defensin 4 | 85 | 0/3 | 63 | 0/3 | ||
21 | Camp | Cathelicidin | 11 | 0/3 | 10 | 0/3 |
Genes that can serve as markers for T-cells (1–11), NK-cells (12–13), B-cells (14–15) and neutrophils (16–21) are listed. For parameters 'P', 'Fold' and 'Direction', see the Gene array section in Methods. Fold changes are given when a gene was called Present (P) in Slc26a4+/- or Slc26a4-/- samples in at least half of the available probes. The direction of the fold change is only given when it exceeded 1.30. Fold changes lower than 1.30 were not considered significant.