Table 3.
3 month | 6 month | ||||||||
---|---|---|---|---|---|---|---|---|---|
High isoflavone diet | Low isoflavone diet | High isoflavone diet | Low isoflavone diet | ||||||
Female | Male | Female | Male | Female | Male | Female | Male | ||
ACh | pEC50 (−log10m) | 7.12 ± 0.17 | 6.93 ± 0.15 | 6.78 ± 0.56 | 6.72 ± 0.36 | 7.24 ± 0.08 | 7.34 ± 0.14 | 6.81 ± 0.16* | 6.73 ± 0.17† |
Max (%) | 89.01 ± 6.83 | 97.87 ± 1.68 | 87.40 ± 9.46 | 97.87 ± 10.06 | 88.91 ± 3.81 | 83.55 ± 7.45 | 84.80 ± 7.45 | 95.34 ± 2.29 | |
NO | pEC50 (−log10m) | 6.01 ± 0.08 | 5.92 ± 0.13 | 5.98 ± 0.11 | 5.77 ± 0.71 | 5.50 ± 0.20 | 4.91 ± 0.21‡ | 5.72 ± 0.16 | 4.97 ± 0.17‡ |
Max (%) | 96.91 ± 3.09 | 99.65 ± 0.35 | 98.44 ± 1.18 | 96.12 ± 2.17 | 92.25 ± 3.56 | 93.17 ± 6.25 | 93.25 ± 4.26 | 92.07 ± 3.3 | |
NA | pEC50 (−log10m) | 6.24 ± 0.17 | 6.12 ± 0.12 | 6.14 ± 0.19 | 5.99 ± 0.04 | 5.74 ± 0.14 | 6.14 ± 0.15‡ | 5.90 ± 0.12 | 6.06 ± 0.12‡ |
Max (mN) | 2.69 ± 0.24 | 3.44 ± 0.36 | 2.65 ± 0.21 | 3.02 ± 0.22 | 3.17 ± 0.24 | 4.04 ± 0.18 ‡ | 2.90 ± 0.28 | 3.70 ± 0.25 ‡ | |
ET-1 | pEC50 (−log10m) | 7.33 ± 0.04 | 7.24 ± 0.07 | 7.20 ± 0.12 | 7.21 ± 0.02 | 7.11 ± 0.12 | 7.30 ± 0.12‡ | 7.26 ± 0.18 | 7.27 ± 0.07‡ |
Max (mN) | 3.33 ± 0.36 | 3.68 ± 0.31 | 3.74 ± 0.21 | 3.77 ± 0.17 | 3.24 ± 0.31 | 3.38 ± 0.14 | 3.38 ± 0.14 | 3.92 ± 0.25 |
Data are presented as the mean ±s.e.m. of 6–10 animals per group.
P < 0.05 low isoflavone females compared with high isoflavone females, ANOVA.
P < 0.05 low isoflavone males compared with high isoflavone males.
P < 0.05 males (both groups) compared with females (both groups), ANOVA.