Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Relation of the application points of the mechanical stress (the location of the Cys mutations (red)) to the secondary-structure elements mentioned in the text. The GMP binding site is colored blue, the ATP binding site green. Ser-99 (homologous to Tyr-78 in yeast GK) is colored magenta for reference. The GK structure is PDB entry 1S4Q.
