Table 1.
Young |
Old |
||||
---|---|---|---|---|---|
Genotype | ALS2+/+ | ALS2−/− | ALS2+/+ | ALS2−/− | Stat |
WBC (106/mL) | 10.0 ± 0.8 | 6.7 ± 0.8 | 6.1 ± 1.1 | 4.8 ± 1.0 | A, g |
Lymphocytes (106/mL) | 6.8 ± 0.8 | 4.4 ± 0.8 | 3.1 ± 1.2 | 2.0 ± 1.0 | A |
Neutrophils (106/mL) | 2.9 ± 0.5 | 1.9 ± 0.5 | 2.6 ± 0.8 | 2.4 ± 0.8 | NS |
Monocytes (106/mL) | 0.225±0.085 | 0.270±0.085 | 0.357±0.120 | 0.315±0.104 | NS |
Basophiles (106/mL) | 0.030±0.017 | 0.015±0.020 | 0.030±0.024 | 0.063±0.020 | NS |
Eosinophiles (106/mL) | 0.007±0.003 | 0.002±0.003 | 0.010±0.004 | 0.008±0.003 | NS |
RBC (109/mL) | 9.7 ± 0.4 | 9.6 ± 0.4 | 9.5 ± 0.5 | 8.6 ± 0.5 | NS |
Platelets (106/mL) | 834 ± 84 | 711 ± 84 | 1041 ± 119 | 919 ± 103 | NS |
Complete blood counts were performed for young (3 months) and older (14 months) ALS2 wild type (ALS2+/+) and ALS2 knockout (ALS2−/−) mice. Data shown are least square means ± standard errors of 6 mice from each of the two young groups and of 4 mice from each of the two old groups after variance analyses. Statistics: A: significant age effect (P<0.01); g: significant genotype effect (P<0.05); NS: no significance.