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. 1999 Sep 14;96(19):10836–10841. doi: 10.1073/pnas.96.19.10836

Figure 4.

Figure 4

ICAM-1 gene expression in diabetic retina. (A) The ribonuclease protection assay shows that retinal ICAM-1 levels were increased significantly 7 days after diabetes induction. Each lane shows the signal from the two retinas of a single animal. The lane labeled “Probes” shows a 100-fold dilution of the full-length ICAM-1 and 18S riboprobes. The lanes labeled “RNase - (0.1)” and “RNase - (0.01)” show the 10-fold and 100-fold dilutions, respectively, of the full-length riboprobes without sample or RNase. (B) When normalized to 18S RNA, the retinal ICAM-1 levels after 7 days of diabetes were 2.2-fold higher (n = 4; P < 0.05) than in the nondiabetic controls. NS = not significant.