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. 2007 Feb 6;3(2):111–119. doi: 10.7150/ijbs.3.111

Figure 5.

Figure 5

Histological changes occur in E19 mouse skin. (A)Methyl green stain. (Left) Mice lacking a functional Elovl4 have a thin and fragile stratum corneum and have a much thinner epidermis and dermis. (Right) Wild type skin has a well developed, thick stratum corneum. Red arrows are drawn across the dermis to show the size difference more clearly. (B) H&E stain. Once again mice lacking a functional Elovl4 (left) have a very thin stratum corneum, epidermis and dermis. Hair cells appear to be normal. (C) H&E stain showing Elovl4270x/270x, Elovl4-/- and wild-type mouse skin. Arrows indicate the SC.