Table 3.
PolyPhen | Deleterious | Not-deleterious | Not predicted |
PANTHER | |||
Deleterious | 1,647 | 2,092 | 73 |
not-deleterious | 1,857 | 11,569 | 310 |
Not predicted | 1,818 | 5,888 | 1,889 |
PolyPhen and PANTHER predictions overlap significantly, with 6.1% of missense mutations categorized as detrimental by both algorithms.