Table 1.
Parameter | Total | Affected | Unaffected | ||
BRCA1 | BRCA2 | BRCA1 | BRCA2 | ||
Number of carriers, n | 789 | 248 | 209 | 218 | 114 |
Age at censoring, years (mean ± SD) | 45.0 ± 11.3 | 42.9 ± 9.6 | 43.9 ± 9.3 | 46.8 ± 13.0 | 48.3 ± 13.0 |
Year of birth, n (%) | |||||
Before 1940 | 247 | 78 (31.5) | 64 (30.6) | 78 (35.8) | 27 (23.7) |
1940 to 1949 | 185 | 69 (27.8) | 61 (29.2) | 40 (18.3) | 15 (13.2) |
1950 to 1959 | 169 | 58 (23.4) | 48 (23.0) | 34 (15.6) | 29 (25.4) |
1960 and after | 188 | 43 (17.3) | 36 (17.2) | 66 (30.3) | 43 (37.7) |
Censoring age, n (%) | |||||
<55 years | 670 | 226 (91.1) | 185 (88.5) | 172 (78.9) | 87 (76.3) |
≥55 years | 119 | 22 (8.9) | 24 (11.5) | 46 (21.1) | 27 (23.7) |
Oophorectomy before censoring age, n | 45 | 5 | 7 | 25 | 8 |