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. 2006 Nov 1;8(6):R64. doi: 10.1186/bcr1617

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Copyright © 2006 Abba et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MUC1 promoter sequence. (a) GATA cis-elements map identified in MUC1 promoter region. (b) DNA sequence showing the TATA box (white box), the transcriptional start site +1 (TSS arrow) and the open reading frame (ORF arrow). Gray boxes indicate putative binding sites for GATA transcription factors showing the following: a GATA1 sequence (-448), a GATA3 sequence (-2395) and four GATA-like sequences (-1446, -1574, -2472, and -2604). Known regulatory elements are underlined (Sp1, STAT1/3, E-MUC1).