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. 2006 Oct 18;121(1):23–34. doi: 10.1007/s00439-006-0260-8

Table 4.

Multiple regression model that explains 73% of the variance in warfarin dose

Predictor SNP P-Value Univariate R2
VKORC1 rs9923231 <0.0001 0.317
CYP2C9 rs1799853 (*2) + rs1057910 (*3) <0.0001 0.159
Age 0.0029 0.092
PROC rs2069919 0.0416 0.090
Bodyweight 0.0075 0.057
EPHX1 rs4653436 0.1016 0.048
Interaction 0.0878 0.036
GGCX rs12714145 0.0260 0.034
ORM1 rs1687390 0.0571 0.026

Univariate R2-values are included for comparison