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Poly-APS activated inward currents in cultured hippocampal neurones. Mean current- voltage relationships plotted under control conditions (broken line) and after activation of inward current by 0.5 μg/ml poly-APS (solid line). Poly-APS application produced an inward cation current with a linear current/voltage relationship. Inset records show currents evoked by step depolarisations to -140 mV from a holding potential of -70 mV under control conditions and in the presence of poly-APS.
