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Poly-APS evoked larger and more sustained inward currents than did the synthetic compounds. Bar chart showing changes in holding current, at a holding voltage of -70 mV, induced by application of poly-APS and samples 1–4. Only poly-APS (open bar A) at 0.5 μg/ml produced a significant inward current (n = 10; P < 0.01 paired t test) compared to resting membrane holding current.
