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. 2007 Feb 2;6:12. doi: 10.1186/1476-4598-6-12

Table 2.

DNA sequence status of KIT exon 17 and expression of KIT in OGCTs

Patient ID Histology of core Bilateral KIT protein expression KIT mutation in codon 816, exon 17
PT-09 DG (w/GB) - GAC to TAC, Asp to Tyr
PT-16 DG + GAC to TAC, Asp to Tyr
PT-49 DG ++ GAC to CAC, Asp to His
PT-52 DG ++ GAC to GTC, Asp to Val
PT-58 DG - GAC to GTC, Asp to Val
PT-04 DG Bilateral ++ wt
GB Bilateral ++ wt
PT-32 DG Bilateral ++ wt
YST Bilateral - wt
PT-35 DG (left ovary) Bilateral ++ wt
DG (right ovary) Bilateral ++ wt
PT-57 GB Bilateral M wt
DG (left ovary) Bilateral ++ wt
DG (right ovary) Bilateral ++ wt
PT-03 DG (w/GB) ++ wt
EC - wt
GB - wt
PT-15 DG M wt
PT-19 DG - wt
PT-27, 39 DG ++ wt
PT-40 DG (w/GB) ++ wt
PT-48 DG + wt
PT-53 CC - wt
DG + wt
PT-28 DG ++ wt
YST - wt
PT-08 YST M wt
PT-20 YST + wt
PT-25,33,43,45,54,55 YST - wt
PT-06,10,18,23,31,34,44,46,47,51 IT - wt
PT-12, 22 IT M wt
PT-36, 37 YST, IT - wt
PT-11, 59, 56 SCC - wt

Staining intensity = '++': >50%, of tumour cells stained; '+': staining in approximately 20–50% of tumour cells; '+-': few cells stained; '-': no positive cells detected. Abbreviations: DG = dysgerminoma; GB = gonadoblastoma; YST = yolk sac tumour; EC = embryonal carcinoma; CC = choriocarcinoma; IT = immature teratoma; OGCT = ovarian germ cell tumour; PT = patient; SCC = small cell carcinoma; M = missing; wt = wild type.