TABLE 1.

Interpretation and summary of sequence changes in D39 (NCTC), D39 (Lilly), and R6 (ATCC)

Sequence change presence in:			Interpretation	Changes
D39 (NCTC)	D39 (Lilly)	R6 (ATCC)		No.	Type
Yesa	Yes	No	Change arose in R6 (ATCC)	81	Seventy-one single-base-pair changes, three small insertions, one large insertion, five small deletions, and one large deletion of part of the cps locus reported previously (50)
Yesb	No	Yes	Change arose in D39 (Lilly)	8	Six single-base-pair changes, one small deletion, and one large deletion
Nob	Yes	Yes	Change arose in D39 (NCTC)	5	Four single-base-pair changes and one small deletion
Yesc	Yes	Yes (resequenced)	Error in published R6 sequence	28	Fourteen in one IS1167 element
Yesd	Yes	NA	Error in published D39 cps sequence	12	One frameshift; eleven single-base-pair changes (six in cps2B)

^aData compiled in Table 2 and Table S1 in the supplemental material.

^bData compiled in Table 4 and Table S2 in the supplemental material.

^cData compiled in Table S4 in the supplemental material.

^dData compiled in Table S5 in the supplemental material.