TABLE 4.
Sequence changes that arose in strain D39 (NCTC) or D39 (Lilly) compared to progenitor strain D39a
| Strain | Changes |
|---|---|
| D39 (NCTC) | ΔG (frameshift); three missense mutationsb; one single base change in IC regionb |
| D39 (Lilly) | Five missense mutationsc; one silent changec; one ΔT (frameshift); one ΔtreP-amiC deletion (7,958 bp) between 14-bp direct repeats (AGTCGCTGTATAAG) |
a
Specific mutations are listed in Table S2 in the supplemental material.
b
There were three transition mutations: one GC to AT (25%) and two AT to GC (50%). There was one transversion mutation: 1 GC to CG (25%).
c
There were four transition mutations: two GC to AT (33%) and two AT to GC (33%). There were two transversion mutations: one AT to CG (17%) and one GC to CG (17%).