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Percentage of influenza virus-specific memory B cells in the circulation before and 30 days (range, 27 to 47 days) after vaccination. Influenza virus-specific memory IgA cells (A and B) and IgG cells (C and D) in adults (A and C) and 5- to 9-year-old children (B and D) before and after LAIV (▪) or TIV (□) vaccination were measured by memory B-cell assay as described in the text. Asterisks indicate a highly significant difference (P < 0.01, GLM and paired t test).
