FIG. 7.

Depletion of cholesterol by MβCD decreases HCVpp entry in Huh-7 cells. (A) Dose-dependent inhibition of HCVpp infection of Huh-7 cells after treatment with 2.5, 5, and 10 mM MβCD. (B) Huh-7 cells were untreated or treated with 10 mM MβCD (MβCD) or 10 mM MβCD plus cholesterol (MβCD+C) and infected with HCVpp or MLVpp. Relative light units (RLU) for each sample were calculated by normalization to mock-treated Huh-7 cells. These are representative data (means ± standard errors of the means) for two independent experiments.