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. 1999 Sep 14;96(19):10857–10862. doi: 10.1073/pnas.96.19.10857

Figure 2.

Figure 2

Expression of insulin gene promoter activity in HIT-T15 cells chronically cultured with various concentrations of NAC and AG. The relative expression of INSCAT to pGL3LUC is normalized to the expression found in the early control passage cells (passages 73–76). Data are presented as mean ± SEM for four independent experiments with triplicate observations at passages 107, 108, 111, and 112 in NAC study and at passages 106, 107, and 108 in AG study (*, P < 0.01 vs. NAC 0; †, P < 0.01 vs. AG 0).